Ukudla kwe-US ukudla kanye nezidakamizwa muva nje kwenze umugqa obalulekile ekulweni nesifo i-Alzheimer's nge-Donanemab, i-monoclonal antibony eyakhiwe ngu-Eli Lilly. Kumakethwa ngaphansi kwegama elithi KISUNLA, lolu thromeka olusha luhlose ukunciphisa ukuqhubeka kwesifo se-Alzheimer's Isifo Sekuqala Ukusiza Umzimba Ukususa I-Amyloid Plaquime Yakha engqondweni - uphawu lwe-Alzheimer's. Lokhu kuvunywa kungagcini nje kuphela umakhalekhukhwini obaluleke kakhulu ocwaningweni lwe-Alzheimer's nocwaningo kodwa futhi uqhakambisa ukubaluleka kokutholwa kwangaphambi kokungenelela nokungenelela.
UKisunla: Isahluko esisha ekwelashweni kwe-Alzheimer
UDonanemab, noma uKisunla, awulona ikhambi le-Alzheimer's kodwa ukhombise imiphumela ethembisayo ezivivinyweni zomtholampilo. Abahlanganyeli abathathe uKisunla bathole ubungozi obuphansi obungu-35% bokuthuthuka kwezifo ngaphezu kwezinyanga eziyi-18 uma kuqhathaniswa nalabo abasendaweni ye-placebo. Lokhu kusho ukuthi iziguli zingaphila ngokuzimela nangokuphepha emisebenzini yansuku zonke isikhathi eside.
Kodwa-ke, kubalulekile ukuqaphela ukuthi ukwelashwa akuyona ngaphandle kwezingozi. Cishe ama-2% ababambiqhaza athole imicimbi emibi kakhulu, kufaka phakathi ama-Amyyyyyyyyyloid ahlobene nemifanekiso yokucabanga (i-Aria), engaholela ekutholeni ama-hemorrhages amancane ebuchosheni. Ngaphandle kwalezi zingcuphe, abeluleki be-FDA babona ukwelashwa kuphephile futhi kusebenza ngempumelelo, kunikezwe izinzuzo zalo ezingaba khona.
Ukubaluleka kokutholwa kusenesikhathi
Ukutholwa kusenesikhathi nokuxilongwa kubalulekile ekwelashweni okusebenzayo kwesifo i-Alzheimer's. UKisunla usebenza kangcono ezigabeni zokuqala uphawu, athutha u-Eli Lilly ukusebenzisana nezinye izinhlangano ukuthuthukisa izindlela zokutholwa kusenesikhathi. Lolu hlelo luqondanisa nesidingo esikhulayo sokungenelela kusenesikhathi, ikakhulukazi njengoba inani lamacala ama-Alzheimer's kulindeleke ukuthi lifinyelele cishe ezigidini eziyi-14 ngo-2060.
Iqhaza Lokunakekelwa Kwasekhaya Ekuphathweni Kwama-Alzheimer's
Njengoba isifo sase-Alzheimer siqhubeka, indima yabanakekeli iba ibalulekile. Abanakekeli Ababukeli basekhaya, abahlinzeka ngokunakekelwa okuqhubekayo nokusekelwa, badlale ingxenye ebalulekile ekuqinisekiseni ukuphepha nenhlala-kahle yeziguli ze-Alzheimer's. Emindenini ephethe i-Alzheimer's ekhaya, imikhiqizo efana naleyo enikelwe yi-Liren Healthcare ingaba usizo.
I-Lireen Healthcare ibheka imikhiqizo ephezulu yezempilo eyenzelwe ukuthuthukisa ukuphepha kwasekhaya nokusebenza kahle kokunakekelwa. Ububanzi bethu bufaka ingcindezi yombhede kanye nesihlaloamaphakethe sensor, Ukuqwashisaamaphager, futhiIzinkinobho Zekholi, konke okubalulekile ekwakheni indawo ephephile nephephile yasekhaya yabadala.
Ukuthuthukisa ukuphepha ekhaya ngemikhiqizo ye-Liren Healthcare
Amaphini we-1.Sprestrere Sensor: Lezi pads zibekwe emibhedeni noma ezihlalweni zokuqapha ukunyakaza futhi zithola lapho umkhawulo evuka, ngaleyo ndlela evimbela ukuwa.
I-2.Alerting Pager: Lawa madivayisi esazisa abanakekeli ngokushesha lapho isidingo esikhulu sidinga usizo, ukuqinisekisa impendulo esheshayo kanye nokunciphisa ubungozi bezingozi.
Izinkinobho ezi-3.Call: Lokhu kuvumela abadala ukuthi bacele usizo ngomshini olula, banikeze ukuthula kwengqondo kuzo zombili iziguli nabanakekeli babo.
Ngokuhlanganisa imikhiqizo yezempilo yeLiren Healthcare ekusethweni kokunakekelwa kwasekhaya, imindeni ingadala indawo ephephile yabathandekayo babo. Kulabo abacabanga ukufaka uhlelo lwe-alamu yezokuphepha, okufaka amaphilisi we-Psressure Sensor kanye nokuqwashisa ngokuxwayisa kungaba ukwengeza okukhulu kwinqubo yokubuka ekhaya.
Ezokuphepha Nokuthula Kwengqondo
Ukufaka uhlelo lokuphepha olufaka imikhiqizo ye-Lire Healthcare ingathuthukisa kakhulu ukuphepha nokuphepha kwesiguli sase-Alzheimer ekhaya. Inqubo yethu yokufakwa kwe-alamu yokuphepha iqondile futhi yenzelwe ukuhlinzeka ukuvikela okuphezulu nokuphazamiseka okuncane.
Ubheke phambili
Imvume kaKisunla imelela intuthuko ebalulekile ekwelashweni kwe-Alzheimer, enikeza ithemba elisha ezigidini ezithintwe yilesi sifo esibhubhisayo. Njengoba siqhubeka nokuhlola futhi sithuthukise ukwelashwa okusha, indima yokunakekelwa kwasekhaya nemikhiqizo emisha efana naleyo evela ku-Liren Healthcare izoba ibaluleke kakhulu ekuphatheni isifo se-Alzheimer's.
Ukuthola imininingwane engaphezulu yokuthi imikhiqizo yezempilo ye-Liren Healthcare ingakusiza kanjani ukudala indawo ephephile yasekhaya yabathandekayo bakho, vakashela iwebhusayithi yethu. Hlala unolwazi ngentuthuko yakamuva ekunakekelweni kwezempilo okuphezulu futhi uthole izixazululo ezinhle kakhulu zokuthuthukisa ikhwalithi yempilo yabadala.
Ukubeka kafushane
Impi yokulwa ne-Alzheimer's isekude kakhulu, kodwa ngempumelelo efana neSisunla kanye nokusekelwa okuqhubekayo kwemikhiqizo yokunakekelwa kwasekhaya evela ezinkampanini ezinjenge-Liren Healthcare, kunethemba lekusasa elingcono. Njengoba samukela lezi zinto ezintsha, ukuqinisekisa ukuphepha nenhlala-kahle yeziguli ze-Alzheimer zihlala zibaluleke kakhulu.
Vakashela iwebhusayithi ye-Liren Healthcare namuhla ukuze ufunde kabanzi ngemikhiqizo yethu nokuthi ungakusiza kanjani ukudala indawo ephephile, evikelekile yekhaya yabathandekayo bakho. Hlala uxhumekile nathi ngezindaba zakamuva nezibuyekezo ekunakekelweni kwezempilo okuphezulu.
Umthombo wezindaba:https://edition.cnn.com/2024/07/02/Hilly-zheimers-donanemab-fda/index.html
ILiren ifuna ukusiza abasabalalisi ukuthi basebenzisane nezimakethe ezibalulekile. Amaqembu anentshisekelo ayakhuthazwa ukuthi axhumane nacustomerservice@lirenltd.comNgemininingwane engaphezulu.
Isikhathi sePosi: Jul-08-2024
